From a technical point of view the board is excellent. You get SLI - if you need it - a fast chipset, two IDE-ports and an excellent four phase VRM. The BIOS and the overclocking results are a mixed bag. Good overclocking results are only possible with high CPU multipliers, only the more expensive CPUs provide these.
The E4xxx series are limited in overclocking, E63x0 and E64x0 will not give you the multiplier to achieve the results all overclockers are looking for. The board has a target price of compareable Intel P965 boards, but with the limited FSB overclocking it isn't the choice for overclocking interested customers.
If you don't care about overclocking, the MSI P6N-SLI Platinum will be a stable, fast, and trouble free board for you. If you don't like the heatpipe or want to use a 3rd party cooling solution, you can buy the non-Platinum Edition, which is about €40 cheaper, but does not feature the "all-solid-capacitor" design. Instead it gives you an additional power-connector for the SLI-setup, the "Platinum" is missing this feature.
MSI should also supply quality cables and a fan that will do the job without producing so much noise. The board is good, but it can be even better, we wish FSB would overclock much better. This is our final conclusion, still 3.73GHz on air cooling is good.
The MSI P6N-SLI Platinum ships for around €135 in Europe.