The Radeon Software Crimson ReLive 17.3.3 driver is solely focused on Mass Effect: Andromeda game, bringing optimizations like multi-GPU profile in DirectX 11, which can be enabled from the command line by using "-RenderDevice.AmdCrossfireEnable 1" as well as fixes texture flickering in the same game that was present in multi-GPU configurations.
Other than Mass Effect: Andromeda, the new Radeon Software Crimson ReLive 17.3.3 driver does not appear to fix anything else, so if this game is not on your list, there is no reason to update the driver.
As always, you can find the new Radeon Software Crimson ReLive 17.3.3 driver as well as full release notes over at AMD's support page.